diff --git a/rust/Cargo.lock.in b/rust/Cargo.lock.in
index 747e8e01d9..0c412e1d5c 100644
--- a/rust/Cargo.lock.in
+++ b/rust/Cargo.lock.in
@@ -114,9 +114,9 @@ checksum = "0c4b4d0bd25bd0b74681c0ad21497610ce1b7c91b1022cd21c80c6fbdd9476b0"
 
 [[package]]
 name = "base64"
-version = "0.13.1"
+version = "0.22.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "9e1b586273c5702936fe7b7d6896644d8be71e6314cfe09d3167c95f712589e8"
+checksum = "72b3254f16251a8381aa12e40e3c4d2f0199f8c6508fbecb9d91f575e0fbb8c6"
 
 [[package]]
 name = "bendy"
diff --git a/rust/Cargo.toml.in b/rust/Cargo.toml.in
index 48e1d1f510..7ec8791ea8 100644
--- a/rust/Cargo.toml.in
+++ b/rust/Cargo.toml.in
@@ -58,7 +58,7 @@ sha1 = "~0.10.5"
 md-5 = "~0.10.1"
 regex = "~1.5.5"
 lazy_static = "~1.4.0"
-base64 = "~0.13.0"
+base64 = "~0.22.1"
 bendy = { version = "~0.3.3", default-features = false }
 asn1-rs = { version = "~0.6.1" }
 ldap-parser = { version = "~0.4.0" }
diff --git a/rust/src/ffi/base64.rs b/rust/src/ffi/base64.rs
index ea72a344c3..e80dd5b528 100644
--- a/rust/src/ffi/base64.rs
+++ b/rust/src/ffi/base64.rs
@@ -1,4 +1,4 @@
-/* Copyright (C) 2021 Open Information Security Foundation
+/* Copyright (C) 2021-2024 Open Information Security Foundation
  *
  * You can copy, redistribute or modify this Program under the terms of
  * the GNU General Public License version 2 as published by the Free
@@ -17,6 +17,7 @@
 
 use std::os::raw::c_uchar;
 use libc::c_ulong;
+use base64::{Engine, engine::general_purpose::STANDARD};
 
 #[repr(C)]
 #[allow(non_camel_case_types)]
@@ -42,7 +43,7 @@ pub unsafe extern "C" fn Base64Encode(
         return Base64ReturnCode::SC_BASE64_INVALID_ARG;
     }
     let input = std::slice::from_raw_parts(input, input_len as usize);
-    let encoded = base64::encode(input);
+    let encoded = STANDARD.encode(input);
     if encoded.len() + 1 > *output_len as usize {
         return Base64ReturnCode::SC_BASE64_OVERFLOW;
     }
diff --git a/rust/src/http2/detect.rs b/rust/src/http2/detect.rs
index b7a43ec522..74bb59223d 100644
--- a/rust/src/http2/detect.rs
+++ b/rust/src/http2/detect.rs
@@ -1,4 +1,4 @@
-/* Copyright (C) 2020 Open Information Security Foundation
+/* Copyright (C) 2020-2024 Open Information Security Foundation
  *
  * You can copy, redistribute or modify this Program under the terms of
  * the GNU General Public License version 2 as published by the Free
@@ -24,6 +24,7 @@ use crate::detect::uint::{detect_match_uint, DetectUintData};
 use std::ffi::CStr;
 use std::str::FromStr;
 use std::rc::Rc;
+use base64::{Engine, engine::general_purpose::STANDARD};
 
 fn http2_tx_has_frametype(
     tx: &mut HTTP2Transaction, direction: Direction, value: u8,
@@ -957,7 +958,7 @@ pub unsafe extern "C" fn rs_http2_tx_set_uri(
 }
 
 fn http2_tx_set_settings(state: &mut HTTP2State, input: &[u8]) {
-    match base64::decode(input) {
+    match STANDARD.decode(input) {
         Ok(dec) => {
             if dec.len() % 6 != 0 {
                 state.set_event(HTTP2Event::InvalidHTTP1Settings);
diff --git a/rust/src/http2/parser.rs b/rust/src/http2/parser.rs
index 519d1b7bfb..239d4e942a 100644
--- a/rust/src/http2/parser.rs
+++ b/rust/src/http2/parser.rs
@@ -32,6 +32,7 @@ use nom7::{Err, IResult};
 use std::fmt;
 use std::str::FromStr;
 use std::rc::Rc;
+use base64::{Engine, engine::general_purpose::STANDARD_NO_PAD};
 
 #[repr(u8)]
 #[derive(Clone, Copy, PartialEq, Eq, FromPrimitive, Debug)]
@@ -762,7 +763,7 @@ pub fn http2_parse_frame_settings(i: &[u8]) -> IResult<&[u8], Vec<HTTP2FrameSett
 
 pub fn doh_extract_request(i: &[u8]) -> IResult<&[u8], Vec<u8>> {
     let (i, _) = tag("/dns-query?dns=")(i)?;
-    match base64::decode(i) {
+    match STANDARD_NO_PAD.decode(i) {
         Ok(dec) => {
             // i is unused
             return Ok((i, dec));
diff --git a/rust/src/jsonbuilder.rs b/rust/src/jsonbuilder.rs
index bc09fb43cc..56fe91fcbd 100644
--- a/rust/src/jsonbuilder.rs
+++ b/rust/src/jsonbuilder.rs
@@ -24,6 +24,7 @@ use std::collections::TryReserveError;
 use std::ffi::CStr;
 use std::os::raw::c_char;
 use std::str::Utf8Error;
+use base64::{Engine, engine::general_purpose::STANDARD};
 
 const INIT_SIZE: usize = 4096;
 
@@ -807,7 +808,7 @@ impl JsonBuilder {
         if self.buf.capacity() < self.buf.len() + encoded_len {
             self.buf.try_reserve(encoded_len)?;
         }
-        base64::encode_config_buf(val, base64::STANDARD, &mut self.buf);
+        STANDARD.encode_string(val, &mut self.buf);
         Ok(self)
     }
 }