diff --git a/README.md b/README.md
index e88162910..63c97c6db 100644
--- a/README.md
+++ b/README.md
@@ -106,6 +106,78 @@ Access Memos at `http://localhost:5230` and complete the initial setup.
 
 **Pro Tip**: The data directory stores all your notes, uploads, and settings. Include it in your backup strategy!
 
+### 🔒 Database Encryption (for SQLite)
+
+<details>
+
+Memos can protect its SQLite database with **SQLCipher** so that the on-disk file is unreadable without a passphrase. This is *encryption at rest*: the server keeps the key in memory while running, so it does not provide end-to-end encryption for clients.
+
+> [!IMPORTANT]
+> Losing the passphrase means losing your data. Store it safely (for example, in a password manager or a hardware secret vault).
+
+#### Enable SQLCipher Builds
+
+- **Docker (recommended)**
+  ```bash
+  docker build \
+    --build-arg CGO_ENABLED=1 \
+    --build-arg MEMOS_BUILD_TAGS="memos_sqlcipher libsqlite3 sqlite_omit_load_extension" \
+    -t memos-sqlcipher \
+    -f scripts/Dockerfile .
+  docker run -d \
+    --name memos \
+    -p 5230:5230 \
+    -v ~/.memos:/var/opt/memos \
+    -e MEMOS_SQLITE_ENCRYPTION_KEY="your-super-secret-key" \
+    memos-sqlcipher
+  ```
+
+- **Manual build**
+  ```bash
+  CGO_ENABLED=1 \
+  CGO_CFLAGS="-I/usr/include/sqlcipher -DSQLITE_HAS_CODEC" \
+  CGO_LDFLAGS="-lsqlcipher" \
+  go build -tags "memos_sqlcipher libsqlite3 sqlite_omit_load_extension" -o memos-sqlcipher ./bin/memos
+  ./memos-sqlcipher --sqlite-encryption-key "your-super-secret-key" ...
+  ```
+
+#### Migration Plan for Existing Deployments
+
+1. **Full backup**
+   ```bash
+   cp ~/.memos/memos_prod.db ~/.memos/memos_prod.db.bak
+   cp ~/.memos/memos_prod.db-wal ~/.memos/memos_prod.db-wal.bak 2>/dev/null || true
+   cp ~/.memos/memos_prod.db-shm ~/.memos/memos_prod.db-shm.bak 2>/dev/null || true
+   ```
+
+2. **Stop every Memos instance** touching the database.
+
+3. **Build the SQLCipher-capable binary or Docker image** using the instructions above. The resulting image already contains the `sqlcipher` CLI.
+
+4. **Convert the database** using the SQLCipher CLI. You can do this without installing anything on the host:
+   ```bash
+   docker run --rm \
+     -v ~/.memos:/data \
+     memos-sqlcipher \
+     sh -c "cd /data && sqlcipher memos_prod.db <<'EOS'\nATTACH DATABASE 'memos_encrypted.db' AS encrypted KEY 'your-super-secret-key';\nSELECT sqlcipher_export('encrypted');\nDETACH DATABASE encrypted;\nEOS"
+   ```
+   If you prefer to run the command directly on the host, install `sqlcipher` (e.g. `brew install sqlcipher`, `apt install sqlcipher`) and execute the same `ATTACH ... sqlcipher_export` sequence locally.
+
+6. **Swap the files**
+   ```bash
+   mv memos_prod.db memos_prod.db.plaintext
+   mv memos_encrypted.db memos_prod.db
+   rm -f memos_prod.db-wal memos_prod.db-shm
+   ```
+
+7. **Start the SQLCipher build of Memos** and pass the same key (`MEMOS_SQLITE_ENCRYPTION_KEY` or `--sqlite-encryption-key`).
+
+8. **Verify the upgrade**
+   - Log in and ensure your memos/attachments are intact.
+   - Confirm the file is encrypted: `sqlite3 memos_prod.db '.tables'` should now print `Error: file is not a database`.
+
+</details>
+
 ## Sponsors
 
 Memos is made possible by the generous support of our sponsors. Their contributions help ensure the project's continued development, maintenance, and growth.
diff --git a/bin/memos/main.go b/bin/memos/main.go
index 48dad202d..a5eabd3d2 100644
--- a/bin/memos/main.go
+++ b/bin/memos/main.go
@@ -25,15 +25,16 @@ var (
 		Short: `An open source, lightweight note-taking service. Easily capture and share your great thoughts.`,
 		Run: func(_ *cobra.Command, _ []string) {
 			instanceProfile := &profile.Profile{
-				Mode:        viper.GetString("mode"),
-				Addr:        viper.GetString("addr"),
-				Port:        viper.GetInt("port"),
-				UNIXSock:    viper.GetString("unix-sock"),
-				Data:        viper.GetString("data"),
-				Driver:      viper.GetString("driver"),
-				DSN:         viper.GetString("dsn"),
-				InstanceURL: viper.GetString("instance-url"),
-				Version:     version.GetCurrentVersion(viper.GetString("mode")),
+				Mode:                viper.GetString("mode"),
+				Addr:                viper.GetString("addr"),
+				Port:                viper.GetInt("port"),
+				UNIXSock:            viper.GetString("unix-sock"),
+				Data:                viper.GetString("data"),
+				Driver:              viper.GetString("driver"),
+				DSN:                 viper.GetString("dsn"),
+				SQLiteEncryptionKey: viper.GetString("sqlite-encryption-key"),
+				InstanceURL:         viper.GetString("instance-url"),
+				Version:             version.GetCurrentVersion(viper.GetString("mode")),
 			}
 			if err := instanceProfile.Validate(); err != nil {
 				panic(err)
@@ -100,6 +101,7 @@ func init() {
 	rootCmd.PersistentFlags().String("data", "", "data directory")
 	rootCmd.PersistentFlags().String("driver", "sqlite", "database driver")
 	rootCmd.PersistentFlags().String("dsn", "", "database source name(aka. DSN)")
+	rootCmd.PersistentFlags().String("sqlite-encryption-key", "", "SQLCipher key used to unlock the SQLite database (requires binary built with memos_sqlcipher)")
 	rootCmd.PersistentFlags().String("instance-url", "", "the url of your memos instance")
 
 	if err := viper.BindPFlag("mode", rootCmd.PersistentFlags().Lookup("mode")); err != nil {
@@ -123,6 +125,9 @@ func init() {
 	if err := viper.BindPFlag("dsn", rootCmd.PersistentFlags().Lookup("dsn")); err != nil {
 		panic(err)
 	}
+	if err := viper.BindPFlag("sqlite-encryption-key", rootCmd.PersistentFlags().Lookup("sqlite-encryption-key")); err != nil {
+		panic(err)
+	}
 	if err := viper.BindPFlag("instance-url", rootCmd.PersistentFlags().Lookup("instance-url")); err != nil {
 		panic(err)
 	}
@@ -132,6 +137,9 @@ func init() {
 	if err := viper.BindEnv("instance-url", "MEMOS_INSTANCE_URL"); err != nil {
 		panic(err)
 	}
+	if err := viper.BindEnv("sqlite-encryption-key", "MEMOS_SQLITE_ENCRYPTION_KEY"); err != nil {
+		panic(err)
+	}
 }
 
 func printGreetings(profile *profile.Profile) {
diff --git a/go.mod b/go.mod
index d0d058c9a..94bd0475b 100644
--- a/go.mod
+++ b/go.mod
@@ -19,6 +19,7 @@ require (
 	github.com/labstack/echo/v4 v4.13.4
 	github.com/lib/pq v1.10.9
 	github.com/lithammer/shortuuid/v4 v4.2.0
+	github.com/mattn/go-sqlite3 v1.14.32
 	github.com/pkg/errors v0.9.1
 	github.com/spf13/cobra v1.10.1
 	github.com/spf13/viper v1.20.1
diff --git a/go.sum b/go.sum
index ccd23bb15..db8973931 100644
--- a/go.sum
+++ b/go.sum
@@ -285,6 +285,8 @@ github.com/mattn/go-isatty v0.0.12/go.mod h1:cbi8OIDigv2wuxKPP5vlRcQ1OAZbq2CE4Ky
 github.com/mattn/go-isatty v0.0.20 h1:xfD0iDuEKnDkl03q4limB+vH+GxLEtL/jb4xVJSWWEY=
 github.com/mattn/go-isatty v0.0.20/go.mod h1:W+V8PltTTMOvKvAeJH7IuucS94S2C6jfK/D7dTCTo3Y=
 github.com/mattn/go-runewidth v0.0.2/go.mod h1:LwmH8dsx7+W8Uxz3IHJYH5QSwggIsqBzpuz5H//U1FU=
+github.com/mattn/go-sqlite3 v1.14.32 h1:JD12Ag3oLy1zQA+BNn74xRgaBbdhbNIDYvQUEuuErjs=
+github.com/mattn/go-sqlite3 v1.14.32/go.mod h1:Uh1q+B4BYcTPb+yiD3kU8Ct7aC0hY9fxUwlHK0RXw+Y=
 github.com/matttproud/golang_protobuf_extensions v1.0.1/go.mod h1:D8He9yQNgCq6Z5Ld7szi9bcBfOoFv/3dc6xSMkL2PC0=
 github.com/miekg/dns v1.0.14/go.mod h1:W1PPwlIAgtquWBMBEV9nkV9Cazfe8ScdGz/Lj7v3Nrg=
 github.com/mitchellh/cli v1.0.0/go.mod h1:hNIlj7HEI86fIcpObd7a0FcrxTWetlwJDGcceTlRvqc=
diff --git a/internal/profile/profile.go b/internal/profile/profile.go
index 8d551d669..72727eb67 100644
--- a/internal/profile/profile.go
+++ b/internal/profile/profile.go
@@ -28,6 +28,8 @@ type Profile struct {
 	// Driver is the database driver
 	// sqlite, mysql
 	Driver string
+	// SQLiteEncryptionKey unlocks SQLCipher-protected SQLite databases when provided.
+	SQLiteEncryptionKey string
 	// Version is the current version of server
 	Version string
 	// InstanceURL is the url of your memos instance.
@@ -88,5 +90,9 @@ func (p *Profile) Validate() error {
 		p.DSN = filepath.Join(dataDir, dbFile)
 	}
 
+	if p.SQLiteEncryptionKey != "" && p.Driver != "sqlite" {
+		return errors.New("sqlite encryption key is only supported when using the sqlite driver")
+	}
+
 	return nil
 }
diff --git a/scripts/Dockerfile b/scripts/Dockerfile
index 38456b37e..469970016 100644
--- a/scripts/Dockerfile
+++ b/scripts/Dockerfile
@@ -1,4 +1,12 @@
 FROM golang:1.25-alpine AS backend
+ARG MEMOS_BUILD_TAGS=""
+ARG CGO_ENABLED=0
+ARG CGO_CFLAGS=""
+ARG CGO_LDFLAGS=""
+ENV CGO_ENABLED=${CGO_ENABLED}
+ENV MEMOS_BUILD_TAGS=${MEMOS_BUILD_TAGS}
+ENV CGO_CFLAGS=${CGO_CFLAGS}
+ENV CGO_LDFLAGS=${CGO_LDFLAGS}
 WORKDIR /backend-build
 COPY go.mod go.sum ./
 RUN go mod download
@@ -7,13 +15,50 @@ COPY . .
 # Refer to `pnpm release` in package.json for the build command.
 RUN --mount=type=cache,target=/go/pkg/mod \
     --mount=type=cache,target=/root/.cache/go-build \
-    go build -ldflags="-s -w" -o memos ./bin/memos/main.go
+    /bin/sh -eux <<'EOF'
+if [ "${CGO_ENABLED}" = "1" ]; then
+    apk add --no-cache --virtual .build-deps build-base pkgconf
+    if printf "%s" "${MEMOS_BUILD_TAGS}" | grep -q "memos_sqlcipher"; then
+        apk add --no-cache --virtual .sqlcipher-build sqlcipher-dev
+        SQLCIPHER_CFLAGS="$(pkg-config --cflags sqlcipher)"
+        SQLCIPHER_LDFLAGS="$(pkg-config --libs sqlcipher)"
+        if [ ! -e /usr/lib/libsqlite3.so ]; then
+            ln -s /usr/lib/libsqlcipher.so /usr/lib/libsqlite3.so
+        fi
+        if [ -z "${CGO_CFLAGS}" ]; then
+            export CGO_CFLAGS="${SQLCIPHER_CFLAGS} -DSQLITE_HAS_CODEC"
+        else
+            export CGO_CFLAGS="${CGO_CFLAGS} ${SQLCIPHER_CFLAGS} -DSQLITE_HAS_CODEC"
+        fi
+        if [ -z "${CGO_LDFLAGS}" ]; then
+            export CGO_LDFLAGS="${SQLCIPHER_LDFLAGS}"
+        else
+            export CGO_LDFLAGS="${CGO_LDFLAGS} ${SQLCIPHER_LDFLAGS}"
+        fi
+    fi
+fi
+
+go build -ldflags="-s -w" -tags="${MEMOS_BUILD_TAGS}" -o memos ./bin/memos/main.go
+
+if [ "${CGO_ENABLED}" = "1" ]; then
+    if apk info -e .sqlcipher-build >/dev/null 2>&1; then
+        apk del .sqlcipher-build
+    fi
+    apk del .build-deps
+fi
+EOF
 
 # Make workspace with above generated files.
 FROM alpine:latest AS monolithic
+ARG MEMOS_BUILD_TAGS=""
 WORKDIR /usr/local/memos
 
 RUN apk add --no-cache tzdata
+RUN if printf "%s" "$MEMOS_BUILD_TAGS" | grep -q "memos_sqlcipher"; then \
+    apk add --no-cache sqlcipher sqlcipher-libs && \
+    if [ -e /usr/lib/libsqlcipher.so ]; then ln -sf /usr/lib/libsqlcipher.so /usr/lib/libsqlite3.so; fi && \
+    if [ -e /usr/lib/libsqlcipher.so.0 ]; then ln -sf /usr/lib/libsqlcipher.so.0 /usr/lib/libsqlcipher.so; fi; \
+  fi
 ENV TZ="UTC"
 
 COPY --from=backend /backend-build/memos /usr/local/memos/
diff --git a/store/db/sqlite/sqlcipher_disabled.go b/store/db/sqlite/sqlcipher_disabled.go
new file mode 100644
index 000000000..ca0a376d1
--- /dev/null
+++ b/store/db/sqlite/sqlcipher_disabled.go
@@ -0,0 +1,32 @@
+//go:build !memos_sqlcipher
+
+package sqlite
+
+import (
+	"database/sql"
+
+	"github.com/pkg/errors"
+
+	"github.com/usememos/memos/internal/profile"
+
+	// Import the pure-Go SQLite driver.
+	_ "modernc.org/sqlite"
+)
+
+func openSQLiteDB(profile *profile.Profile) (*sql.DB, error) {
+	if profile.SQLiteEncryptionKey != "" {
+		return nil, errors.New("sqlite encryption key provided but binary is not built with SQLCipher support; rebuild with -tags memos_sqlcipher")
+	}
+
+	sqliteDB, err := sql.Open(sqliteModernDriver, profile.DSN)
+	if err != nil {
+		return nil, errors.Wrapf(err, "failed to open db with dsn: %s", profile.DSN)
+	}
+
+	if err := configureSQLiteConnection(sqliteDB); err != nil {
+		sqliteDB.Close()
+		return nil, err
+	}
+
+	return sqliteDB, nil
+}
diff --git a/store/db/sqlite/sqlcipher_enabled.go b/store/db/sqlite/sqlcipher_enabled.go
new file mode 100644
index 000000000..d6b65f9e9
--- /dev/null
+++ b/store/db/sqlite/sqlcipher_enabled.go
@@ -0,0 +1,49 @@
+//go:build memos_sqlcipher
+
+package sqlite
+
+import (
+	"database/sql"
+	"fmt"
+	"strings"
+
+	"github.com/pkg/errors"
+
+	"github.com/usememos/memos/internal/profile"
+
+	// Import the CGO-backed SQLCipher-compatible SQLite driver.
+	_ "github.com/mattn/go-sqlite3"
+)
+
+func openSQLiteDB(profile *profile.Profile) (*sql.DB, error) {
+	sqliteDB, err := sql.Open(sqliteCipherDriver, profile.DSN)
+	if err != nil {
+		return nil, errors.Wrapf(err, "failed to open db with dsn: %s", profile.DSN)
+	}
+
+	if err := applySQLiteEncryptionKey(sqliteDB, profile.SQLiteEncryptionKey); err != nil {
+		sqliteDB.Close()
+		return nil, err
+	}
+
+	if err := configureSQLiteConnection(sqliteDB); err != nil {
+		sqliteDB.Close()
+		return nil, err
+	}
+
+	return sqliteDB, nil
+}
+
+func applySQLiteEncryptionKey(db *sql.DB, key string) error {
+	if key == "" {
+		return nil
+	}
+
+	escapedKey := strings.ReplaceAll(key, "'", "''")
+	pragma := fmt.Sprintf("PRAGMA key = '%s'", escapedKey)
+	if _, err := db.Exec(pragma); err != nil {
+		return errors.Wrap(err, "failed to apply sqlite encryption key; verify the binary is linked against SQLCipher")
+	}
+
+	return nil
+}
diff --git a/store/db/sqlite/sqlite.go b/store/db/sqlite/sqlite.go
index 3b4a30f8d..31737fee4 100644
--- a/store/db/sqlite/sqlite.go
+++ b/store/db/sqlite/sqlite.go
@@ -3,12 +3,10 @@ package sqlite
 import (
 	"context"
 	"database/sql"
+	"fmt"
 
 	"github.com/pkg/errors"
 
-	// Import the SQLite driver.
-	_ "modernc.org/sqlite"
-
 	"github.com/usememos/memos/internal/profile"
 	"github.com/usememos/memos/store"
 )
@@ -21,29 +19,21 @@ type DB struct {
 // NewDB opens a database specified by its database driver name and a
 // driver-specific data source name, usually consisting of at least a
 // database name and connection information.
+const (
+	sqliteBusyTimeout  = 10000
+	sqliteModernDriver = "sqlite"
+	sqliteCipherDriver = "sqlite3"
+)
+
 func NewDB(profile *profile.Profile) (store.Driver, error) {
 	// Ensure a DSN is set before attempting to open the database.
 	if profile.DSN == "" {
 		return nil, errors.New("dsn required")
 	}
 
-	// Connect to the database with some sane settings:
-	// - No shared-cache: it's obsolete; WAL journal mode is a better solution.
-	// - No foreign key constraints: it's currently disabled by default, but it's a
-	// good practice to be explicit and prevent future surprises on SQLite upgrades.
-	// - Journal mode set to WAL: it's the recommended journal mode for most applications
-	// as it prevents locking issues.
-	//
-	// Notes:
-	// - When using the `modernc.org/sqlite` driver, each pragma must be prefixed with `_pragma=`.
-	//
-	// References:
-	// - https://pkg.go.dev/modernc.org/sqlite#Driver.Open
-	// - https://www.sqlite.org/sharedcache.html
-	// - https://www.sqlite.org/pragma.html
-	sqliteDB, err := sql.Open("sqlite", profile.DSN+"?_pragma=foreign_keys(0)&_pragma=busy_timeout(10000)&_pragma=journal_mode(WAL)")
+	sqliteDB, err := openSQLiteDB(profile)
 	if err != nil {
-		return nil, errors.Wrapf(err, "failed to open db with dsn: %s", profile.DSN)
+		return nil, err
 	}
 
 	driver := DB{db: sqliteDB, profile: profile}
@@ -51,6 +41,20 @@ func NewDB(profile *profile.Profile) (store.Driver, error) {
 	return &driver, nil
 }
 
+func configureSQLiteConnection(db *sql.DB) error {
+	pragmas := []string{
+		"PRAGMA foreign_keys = OFF",
+		fmt.Sprintf("PRAGMA busy_timeout = %d", sqliteBusyTimeout),
+		"PRAGMA journal_mode = WAL",
+	}
+	for _, pragma := range pragmas {
+		if _, err := db.Exec(pragma); err != nil {
+			return errors.Wrapf(err, "failed to execute %s", pragma)
+		}
+	}
+	return nil
+}
+
 func (d *DB) GetDB() *sql.DB {
 	return d.db
 }